Low-level light stimulates excisional wound healing in mice

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Low-level light stimulates excisional wound healing in mice.

BACKGROUND Low levels of laser or non-coherent light, termed low-level light therapy (LLLT) have been reported to accelerate some phases of wound healing, but its clinical use remains controversial. METHODS A full thickness dorsal excisional wound in mice was treated with a single exposure to light of various wavelengths and fluences 30 minutes after wounding. Wound areas were measured until ...

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Additive enhancement of wound healing in diabetic mice by low level light and topical CoQ10

Diabetes, a highly prevalent disease that affects 9.3% of Americans, often leads to severe complications and slow wound healing. Preclinical studies have suggested that low level light therapy (LLLT) can accelerate wound healing in diabetic subjects, but significant improvements must be made to overcome the absence of persuasive evidence for its clinical use. We demonstrate here that LLLT can b...

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Effect of Low Level Laser Therapy on the Surgical Wound Healing in Hamster

Background and Objectives: Accelerating wound healing is a very important factor for patients to return to ordinary life. Laser seems to have positive effect on cutaneous wound healing. This study aimed to investigate the effect of red light laser 630 nm on cutaneous surgical wound in hamster and to compare outcomes such as angiogenesis, number of fibroblasts and collagen form...

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Recombinant Basic Fibroblast Growth Factor Stimulates Wound Healing in Healing-impaired dbldb Mice

The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/Ksj AM mice, and their normal (db/+) littermates with a punch biopsy instrument . Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological sect...

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Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice

The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/KsJ db/db mice, and their normal (db/+) littermates with a punch biopsy instrument. Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological se...

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ژورنال

عنوان ژورنال: Lasers in Surgery and Medicine

سال: 2007

ISSN: 0196-8092,1096-9101

DOI: 10.1002/lsm.20549